IL19 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human IL19 protein.
Immunogen
IL19 (NP_715639.1, 1 a.a. ~ 215 a.a) full-length human protein.
Sequence
MCTEGAFPHRSACSLPLTHVHTHIHVCVPVLWGSVPRGMKLQCVSLWLLGTILILCSVDNHGLRRCLISTDMHHIEESFQEIKRAIQAKDTFPNVTILSTLETLQIIKPLDVCCVTKNLLAFYVDRVFKDHQEPNPKILRKISSIANSFLYMQKTLRQCQEQRQCHCRQEATNATRVIHDNYDQLEVHAAAIKSLGELDVFLAWINKNHEVMFSA
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (69)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of IL19 expression in transfected 293T cell line (H00029949-T02) by IL19 MaxPab polyclonal antibody.
Lane 1: IL19 transfected lysate(24.60 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — IL19
Entrez GeneID
29949GeneBank Accession#
NM_153758Protein Accession#
NP_715639.1Gene Name
IL19
Gene Alias
IL-10C, MDA1, NG.1, ZMDA1
Gene Description
interleukin 19
Omim ID
605687Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq
Other Designations
melanoma differentiation associated protein-like protein
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Pathway
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Disease
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