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DNMT3L 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00029947-T02
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-DNMT3L full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 43.5
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-DNMT3L antibody (H00029947-B01P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00029947-T02
    DNMT3L transfected lysate.
    Western Blot
    QC Testing of H00029947-T02
    Lane 1: DNMT3L transfected lysate ( 43.50 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Gene Name:
  • DNMT3L
  • Gene Alias:
  • MGC1090
  • Gene Description:
  • DNA (cytosine-5-)-methyltransferase 3-like
  • Gene Summary:
  • CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases. This protein is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, this protein does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and it is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternative splicing results in two transcript variants. An additional splice variant has been described but its biological validity has not been determined. [provided by RefSeq
  • Other Designations:
  • cytosine-5-methyltransferase 3-like protein,human cytosine-5-methyltransferase 3-like protein
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