DNMT3L purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
DNMT3L MaxPab polyclonal antibody. Western Blot analysis of DNMT3L expression in human pancreas.
Western Blot (Transfected lysate)
Western Blot analysis of DNMT3L expression in transfected 293T cell line (H00029947-T02) by DNMT3L MaxPab polyclonal antibody.
Lane 1: DNMT3L transfected lysate(42.46 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human DNMT3L protein.
Immunogen
DNMT3L (AAH02560.1, 1 a.a. ~ 386 a.a) full-length human protein.
Sequence
MAAIPALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQVHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFYDRESENPLEMFETVPVWRRQPVRVLSLFEDIKKELTSLGFLESGSDPGQLKHVVDVTDTVRKDVEEWGPFDLVYGATPPLGHTCDRPPSWYLFQFHRLLQYARPKPGSPGPFFWMFVDNLVLNKEDLDVASRFLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSRHWALVSEEELSLLAQNKQSSKLAAKWPTKLVKNCFLPLREYFKYFSTELTSSL
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
DNMT3L MaxPab polyclonal antibody. Western Blot analysis of DNMT3L expression in human pancreas.Western Blot (Transfected lysate)
Western Blot analysis of DNMT3L expression in transfected 293T cell line (H00029947-T02) by DNMT3L MaxPab polyclonal antibody.
Lane 1: DNMT3L transfected lysate(42.46 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — DNMT3L
Entrez GeneID
29947GeneBank Accession#
BC002560.2Protein Accession#
AAH02560.1Gene Name
DNMT3L
Gene Alias
MGC1090
Gene Description
DNA (cytosine-5-)-methyltransferase 3-like
Omim ID
606588Gene Ontology
HyperlinkGene Summary
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases. This protein is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, this protein does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and it is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternative splicing results in two transcript variants. An additional splice variant has been described but its biological validity has not been determined. [provided by RefSeq
Other Designations
cytosine-5-methyltransferase 3-like protein|human cytosine-5-methyltransferase 3-like protein
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Interactome
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Pathway
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Disease
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