SERTAD3 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human SERTAD3 full-length ORF ( NP_037500.2, 1 a.a. - 196 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MVGGLKRKHSDLEEEEERWEWSPAGLQSYQQALLRISLDKVQRSLGPRAPSLRRHVLIHNTLQQLQAALRLAPAPALPPEPLFLGEEDFSLSATIGSILRELDTSMDGTEPPQNPVTPLGLQNEVPPQPDPVFLEALSSRYLGDSGLDDFFLDIDTSAVEKEPARAPPEPPHNLFCAPGSWEWNELDHIMEIILGS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
48.2
Interspecies Antigen Sequence
Mouse (85); Rat (84)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SERTAD3
Entrez GeneID
29946GeneBank Accession#
NM_013368.2Protein Accession#
NP_037500.2Gene Name
SERTAD3
Gene Alias
RBT1
Gene Description
SERTA domain containing 3
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene was identified in a yeast two-hybrid assay employing the second subunit of human replication protein A as bait. It is localized to the nucleus and its expression is significantly higher in cancer cell lines compared to normal cell lines. This protein has also been shown to be a strong transcriptional co-activator. Alternative splicing has been observed at this locus and two variants, both encoding the same protein, have been identified. [provided by RefSeq
Other Designations
RPA-binding trans-activator
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Interactome
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