SEC61A1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human SEC61A1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human SEC61A1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human SEC61A1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — SEC61A1
Entrez GeneID
29927GeneBank Accession#
SEC61A1Gene Name
SEC61A1
Gene Alias
HSEC61, SEC61, SEC61A
Gene Description
Sec61 alpha 1 subunit (S. cerevisiae)
Omim ID
609213Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits. [provided by RefSeq
Other Designations
Sec61 alpha 1 subunit|Sec61 alpha-1|protein transport protein SEC61 alpha subunit|sec61 homolog
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Interactome
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Pathway
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