GMPPB monoclonal antibody (M07), clone 2B5
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GMPPB.
Immunogen
GMPPB (NP_037466, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MKALILVGGYGTRLRPLTLSTPKPLVDFCNKPILLHQVEALAAAGVDHVILAVSYMSQVLEKEMKAQEQRLGIRISMSHEEEPLGTAGPLALARDLLSETADPFFVLNSD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
GMPPB monoclonal antibody (M07), clone 2B5 Western Blot analysis of GMPPB expression in HepG2 ( Cat # L019V1 ).Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to GMPPB on formalin-fixed paraffin-embedded human adrenal gland. [antibody concentration 3 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GMPPB is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — GMPPB
Entrez GeneID
29925GeneBank Accession#
NM_013334Protein Accession#
NP_037466Gene Name
GMPPB
Gene Alias
KIAA1851
Gene Description
GDP-mannose pyrophosphorylase B
Gene Ontology
HyperlinkGene Summary
This gene is thought to encode a GDP-mannose pyrophosphorylase. The encoded protein catalyzes the conversion of mannose-1-phosphate and GTP to GDP-mannose, a reaction involved in the production of N-linked oligosaccharides. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq
Other Designations
mannose-1-phosphate guanylyltransferase
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Interactome
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Pathway
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Disease
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