SNX15 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
SNX15 transfected lysate.
Western Blot
Lane 1: SNX15 transfected lysate ( 38.3 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SNX15 full-length
Host
Human
Theoretical MW (kDa)
37.73
Interspecies Antigen Sequence
Mouse (88); Rat (86)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SNX15 antibody (H00029907-B02) by Western Blots.
SDS-PAGE Gel
SNX15 transfected lysate.
Western Blot
Lane 1: SNX15 transfected lysate ( 38.3 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SNX15
Entrez GeneID
29907GeneBank Accession#
NM_013306Protein Accession#
NP_037438Gene Name
SNX15
Gene Alias
HSAF001435
Gene Description
sorting nexin 15
Omim ID
605964Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. This gene encodes two transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000035515|clone iota unknown protein
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