SNX15 MaxPab mouse polyclonal antibody (B01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of SNX15 expression in transfected 293T cell line (H00029907-T01) by SNX15 MaxPab polyclonal antibody.
Lane 1: SNX15 transfected lysate(37.62 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human SNX15 protein.
Immunogen
SNX15 (AAH09897.1, 1 a.a. ~ 342 a.a) full-length human protein.
Sequence
MSRQAKDDFLRHYTVSDPRTHPKGYTEYKVTAQFISKKDPEDVKEVVVWKRYSDFRKLHGDLAYTHRNLFRRLEEFPAFPRAQVFGRFEASVIEERRKGAEDLLRFTVHIPALNNSPQLKEFFRGGEVTRPLEVSRDLHILPPPLIPTPPPDDPRLSQLLPAERRGLEELEVPVDPPPSSPAQEALDLLFNCESTEEASGSPARGPLTEAELALFDPFSKEEGAAPSPTHVAELATMEVESARLDQEPWEPGGQEEEEDGEGGPTPAYLSQATELITQALRDEKAGAYAAALQGYRDGVHVLLQGVPSDPLPARQEGVKKKAAEYLKRAEEILRLHLSQLPP
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88); Rat (86)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SNX15 expression in transfected 293T cell line (H00029907-T01) by SNX15 MaxPab polyclonal antibody.
Lane 1: SNX15 transfected lysate(37.62 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — SNX15
Entrez GeneID
29907GeneBank Accession#
BC009897.1Protein Accession#
AAH09897Gene Name
SNX15
Gene Alias
HSAF001435
Gene Description
sorting nexin 15
Omim ID
605964Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. This gene encodes two transcript variants encoding distinct isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000035515|clone iota unknown protein
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