CNOT7 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (37.11 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant CNOT7.
Immunogen
CNOT7 (NP_037486, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag.
Sequence
MKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADYQYQLLRCNVDLLKIIQLGLTFMNEQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSGIQF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — CNOT7
Entrez GeneID
29883GeneBank Accession#
NM_013354Protein Accession#
NP_037486Gene Name
CNOT7
Gene Alias
CAF1, hCAF-1
Gene Description
CCR4-NOT transcription complex, subunit 7
Omim ID
604913Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
BTG1 binding factor 1|carbon catabolite repressor protein (CCR4)-associative factor 1
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Interactome
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Pathway
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Publication Reference
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hCAF1/CNOT7 regulates interferon signalling by targeting STAT1.
Chapat C, Kolytcheff C, Le Romancer M, Auboeuf D, De La Grange P, Chettab K, Sentis S, Corbo L.
THE EMBO JOURNAL 2013 Mar; 32(5):688.
Application：WB-IP,IFA, Human, MCF-7 cells.
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hCAF1/CNOT7 regulates interferon signalling by targeting STAT1.
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