ANAPC2 monoclonal antibody (M02), clone 7F2
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More Files
- More Functions
Western Blot detection against Immunogen (37.51 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ANAPC2.
Immunogen
ANAPC2 (NP_037498, 716 a.a. ~ 822 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
IEEERPQDRDNMVLIDSDDESDSGMASQADQKEEELLLFWTYIQAMLTNLESLSLDRIYNMLRMFVVTGPALAEIDLQELQGYLQKKVRDQQLVYSAGVYRLPKNCS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.51 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — ANAPC2
Entrez GeneID
29882GeneBank Accession#
NM_013366Protein Accession#
NP_037498Gene Name
ANAPC2
Gene Alias
APC2, RP11-350O14.5
Gene Description
anaphase promoting complex subunit 2
Omim ID
606946Gene Ontology
HyperlinkGene Summary
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, which may also be involved in ubiquitin-mediated degradation. [provided by RefSeq
Other Designations
OTTHUMP00000022692|anaphase-promoting complex subunit 2
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Interactome
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Pathway
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