ICOS monoclonal antibody (M02), clone 3G4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ICOS.
Immunogen
ICOS (NP_036224.1, 21 a.a. ~ 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
EINGSANYEMFIFHNGGVQILCKYPDIVQQFKMQLLKGGQILCDLTKTKGSGNTVSIKSLKFCHSQLSNNSVSFFLYNLDHSHANYYFCNLSIFDPPPFKVTLTGGYLHIYESQLCCQLK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (70); Rat (69)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.83 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged ICOS is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — ICOS
Entrez GeneID
29851GeneBank Accession#
NM_012092.2Protein Accession#
NP_036224.1Gene Name
ICOS
Gene Alias
AILIM, CD278, MGC39850
Gene Description
inducible T-cell co-stimulator
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation. [provided by RefSeq
Other Designations
activation-inducible lymphocyte immunomediatory molecule|inducible costimulator
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Interactome
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Pathway
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Disease
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