SENP1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human SENP1 partial ORF ( NP_055369, 544 a.a. - 643 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
KNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (97)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SENP1
Entrez GeneID
29843GeneBank Accession#
NM_014554Protein Accession#
NP_055369Gene Name
SENP1
Gene Alias
SuPr-2
Gene Description
SUMO1/sentrin specific peptidase 1
Gene Ontology
HyperlinkGene Summary
The covalent modification of proteins by the small ubiquitin (UBB; MIM 191339)-like protein SUMO (see SUMO1, MIM 601912) is implicated in the regulation of nucleocytoplasmic transport, genomic stability, gene transcription, and other processes. Sumoylation is catalyzed on target lysine residues by a multienzyme process and is reversed by desumoylating enzymes such as SENP1 (Yamaguchi et al., 2005 [PubMed 15923632]).[supplied by OMIM
Other Designations
SUMO1/sentrin specific protease 1|sentrin/SUMO-specific protease|sentrin/SUMO-specific protease 1
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