NCAPH2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human NCAPH2 full-length ORF ( NP_689512.1, 1 a.a. - 555 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MNFIEAALLIQGSACVYSKKVEYLYSLVYQALDFISGKRRAKQLSSVQEDRANGVASSGVPQEAENEFLSLDDFPDSRTNVDLKNDQTPSEVLIIPLLPMALVAPDEMEKNNNPLYSRQGEVLASRKDFRMNTCVPHPRGAFMLEPEGMSPMEPAGVSPMPGTQKDTGRTEEQPMEVSVCRSPVPALGFSQEPGPSPEGPMPLGGGEDEDAEEAVELPEASAPKAALEPKESRSPQQSAALPRRYMLREREGAPEPASCVKETPDPWQSLDPFDSLESKPFKKGRPYSVPPCVEEALGQKRKRKGAAKLQDFHQWYLAAYADHADSRRLRRKGPSFADMEVLYWTHVKEQLETLRKLQRREVAEQWLRPAEEDHLEDSLEDLGAADDFLEPEEYMEPEGADPREAADLDAVPMSLSYEELVRRNVELFIATSQKFVQETELSQRIRDWEDTVQPLLQEQEQHVPFDIHTYGDQLVSRFPQLNEWCPFAELVAGQPAFEVCRSMLASLQLANDYTVEITQQPGLEMAVDTMSLRLLTHQRAHKRFQTYAAPSMAQP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
88.9
Interspecies Antigen Sequence
Mouse (77); Rat (78)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — NCAPH2
Entrez GeneID
29781GeneBank Accession#
NM_152299.1Protein Accession#
NP_689512.1Gene Name
NCAPH2
Gene Alias
384D8-2, 384D8_6, CAP-H2, MGC15858, MGC18000, MGC2455, MGC4133, MGC5305, MGC8640, hCAP-H2
Gene Description
non-SMC condensin II complex, subunit H2
Omim ID
611230Gene Ontology
HyperlinkGene Summary
Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPH2 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003 [PubMed 14532007]).[supplied by OMIM
Other Designations
CAP-H2 subunit of the condensin II complex|OTTHUMP00000196603|kleisin beta
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Interactome
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Disease
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Publication Reference
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Mps1 phosphorylation of condensin II controls chromosome condensation at the onset of mitosis.
Kagami Y, Nihira K, Wada S, Ono M, Honda M, Yoshida K.
The Journal of Cell Biology 2014 Jun; 205(6):781.
Application：KA, Recombinant protein.
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Mps1 phosphorylation of condensin II controls chromosome condensation at the onset of mitosis.
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