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BLNK 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00029760-T03
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-BLNK full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 50.5
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-BLNK antibody (H00029760-D01P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00029760-T03
    BLNK transfected lysate.
    Western Blot
    QC Testing of H00029760-T03
    Lane 1: BLNK transfected lysate ( 50.50 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Gene Name:
  • BLNK
  • Gene Alias:
  • BASH,BLNK-S,LY57,MGC111051,SLP-65,SLP65
  • Gene Description:
  • B-cell linker
  • Gene Summary:
  • This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • B cell linker protein,B-cell adapter containing a SH2 domain protein,B-cell adapter containing a Src homology 2 domain protein,OTTHUMP00000020167,Src homology 2 domain-containing leukocyte protein of 65 kDa
  • Interactome
  • Interactome
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