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UHRF1 (Human) Recombinant Protein (Q01)

  • Catalog # : H00029128-Q01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Human UHRF1 partial ORF ( NP_037414, 694 a.a. - 793 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 36.74
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00029128-Q01
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Gene Name:
  • UHRF1
  • Gene Alias:
  • FLJ21925,ICBP90,MGC138707,Np95,RNF106,hNP95
  • Gene Description:
  • ubiquitin-like with PHD and ring finger domains 1
  • Gene Summary:
  • This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • E3 ubiquitin-protein ligase UHRF1,RING finger protein 106,inverted CCAAT box-binding protein of 90 kDa,nuclear zinc finger protein Np95,transcription factor ICBP90,ubiquitin-like, containing PHD and RING finger domains, 1
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