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Last updated: 2017/7/16

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PYCARD Pre-design Chimera RNAi

  • Catalog # : H00029108-R01
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  • Specification
  • Product Description:
  • Homo sapiens PYD and CARD domain containing (PYCARD), transcript variant 1, mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_013258
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • PYCARD
  • Gene Alias:
  • ASC,CARD5,MGC10332,TMS,TMS-1,TMS1
  • Gene Description:
  • PYD and CARD domain containing
  • Gene Summary:
  • This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • apoptosis-associated speck-like protein containing a CARD,caspase recruitment domain protein 5,target of methylation-induced silencing-1
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