RNASEN (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human RNASEN partial ORF ( NP_037367.2, 1099 a.a. - 1196 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
ETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGHNQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAEELGM
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.52
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — RNASEN
Entrez GeneID
29102GeneBank Accession#
NM_013235Protein Accession#
NP_037367.2Gene Name
RNASEN
Gene Alias
DROSHA, ETOHI2, HSA242976, RANSE3L, RN3, RNASE3L
Gene Description
ribonuclease type III, nuclear
Omim ID
608828Gene Ontology
HyperlinkGene Summary
Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003 [PubMed 14508493]).[supplied by OMIM
Other Designations
drosha, double-stranded RNA-specific endoribonuclease|drosha, ribonuclease type III|nuclear RNase III Drosha|putative protein p241 which interacts with transcription factor Sp1|putative ribonuclease III|ribonuclease III, nuclear
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Interactome
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Disease
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