RGC32 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human RGC32 partial ORF ( NP_054778, 28 a.a. - 117 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
ERHFHYEEHLERMKRRSSASVSDSSGFSDSESADSLYRNSFSFSDEKLNSPTDSTPALLSATVTPQKAKLGDTKELEAFIADLDKTLASM
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
35.64
Interspecies Antigen Sequence
Mouse (87); Rat (91)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — C13orf15
Entrez GeneID
28984GeneBank Accession#
NM_014059Protein Accession#
NP_054778Gene Name
C13orf15
Gene Alias
KIAA0564, MGC87338, RGC-32, RGC32, bA157L14.2
Gene Description
chromosome 13 open reading frame 15
Omim ID
610077Gene Ontology
HyperlinkGene Summary
This gene is thought to regulate cell cycle progression. It is induced by p53 in response to DNA damage, or by sublytic levels of complement system proteins that result in activation of the cell cycle. The encoded protein localizes to the cytoplasm during interphase and to centrosomes during mitosis. The protein forms a complex with polo-like kinase 1. The protein also translocates to the nucleus in response to treatment with complement system proteins, and can associate with and increase the kinase activity of cell division cycle 2 protein. In different assays and cell types, overexpression of this protein has been shown to activate or suppress cell cycle progression. [provided by RefSeq
Other Designations
OTTHUMP00000018322|response gene to complement 32
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Interactome
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Disease
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