OSTM1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human OSTM1 partial ORF ( NP_054747.2, 183 a.a. - 282 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
SNSTVYFLNLFNHTLTCFEHNLQGNAHSLLQTKNYSEVCKNCREAYKTLSSLYSEMQKMNELENKAEPGTHLCIDVEDAMNITRKLWSRTFNCSVPCSDT
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (80); Rat (82)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — OSTM1
Entrez GeneID
28962GeneBank Accession#
NM_014028Protein Accession#
NP_054747.2Gene Name
OSTM1
Gene Alias
GIPN, GL, HSPC019, OPTB5
Gene Description
osteopetrosis associated transmembrane protein 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis. [provided by RefSeq
Other Designations
GAIP-interacting protein N terminus|OTTHUMP00000016938|grey-lethal osteopetrosis
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Interactome
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Disease
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