OSTM1 monoclonal antibody (M05), clone 4H1
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged OSTM1 is 1 ng/ml as a capture antibody.
Western Blot detection against Immunogen (36.74 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant OSTM1.
Immunogen
OSTM1 (NP_054747.2, 183 a.a. ~ 282 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SNSTVYFLNLFNHTLTCFEHNLQGNAHSLLQTKNYSEVCKNCREAYKTLSSLYSEMQKMNELENKAEPGTHLCIDVEDAMNITRKLWSRTFNCSVPCSDT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (80); Rat (82)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged OSTM1 is 1 ng/ml as a capture antibody.ELISA
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Gene Info — OSTM1
Entrez GeneID
28962GeneBank Accession#
NM_014028Protein Accession#
NP_054747.2Gene Name
OSTM1
Gene Alias
GIPN, GL, HSPC019, OPTB5
Gene Description
osteopetrosis associated transmembrane protein 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis. [provided by RefSeq
Other Designations
GAIP-interacting protein N terminus|OTTHUMP00000016938|grey-lethal osteopetrosis
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Interactome
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Disease
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