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PPP2R3B rabbit monoclonal antibody

  • Catalog # : H00028227-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PPP2R3B peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PPP2R3B is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PPP2R3B peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Gene Name:
  • PPP2R3B
  • Gene Alias:
  • NY-REN-8,PPP2R3L,PPP2R3LY,PR48
  • Gene Description:
  • protein phosphatase 2 (formerly 2A), regulatory subunit B'', beta
  • Gene Summary:
  • Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the beta subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • NY-REN-8 antigen,OTTHUMP00000022820,PP2A B'' subunit PR48,PP2A, subunit B, PR48 isoform,protein phosphatase 2, regulatory subunit B'', beta,serine/threonine protein phosphatase 2A, 48kDa regulatory subunit B
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