STK39 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human STK39 partial ORF ( NP_037365, 362 a.a. - 461 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
RAKKVRRVPGSSGHLHKTEDGDWEWSDDEMDEKSEEGKAAFSQEKSRRVKEENPEIAVSASTIPEQIQSLSVHDSQGPPNANEDYREASSCAVNLVLRLR
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (94); Rat (96)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — STK39
Entrez GeneID
27347GeneBank Accession#
NM_013233Protein Accession#
NP_037365Gene Name
STK39
Gene Alias
DCHT, DKFZp686K05124, PASK, SPAK
Gene Description
serine threonine kinase 39 (STE20/SPS1 homolog, yeast)
Omim ID
607648Gene Ontology
HyperlinkGene Summary
This gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq
Other Designations
Ste20-like protein kinase|proline-alanine-rich STE20-related kinase|small intestine SPAK-like kinase
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Interactome
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Disease
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Publication Reference
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Mining the pre-diagnostic antibody repertoire of TgMMTV-neu mice to identify autoantibodies useful for the early detection of human breast cancer.
Mao J, Ladd J, Gad E, Rastetter L, Johnson MM, Marzbani E, Childs JS, Lu H, Dang Y, Broussard E, Stanton SE, Hanash SM, Disis ML.
Journal of Translational Medicine 2014 May; 12:121.
Application：ELISA, Mouse, Serum.
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Mining the pre-diagnostic antibody repertoire of TgMMTV-neu mice to identify autoantibodies useful for the early detection of human breast cancer.
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