KCNMB4 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a partial-length human KCNMB4 DNA using DNAx™ Immune technology.
Technology
Immunogen
Extracellular membrane domain (ECD) human DNA
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — KCNMB4
Entrez GeneID
27345GeneBank Accession#
NM_014505.4Protein Accession#
NP_055320.4Gene Name
KCNMB4
Gene Alias
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Gene Description
potassium large conductance calcium-activated channel, subfamily M, beta member 4
Omim ID
605223Gene Ontology
HyperlinkGene Summary
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit. [provided by RefSeq
Other Designations
calcium-activated potassium channel beta 4 subunit|large conductance calcium-dependent potassium ion channel beta 4 subunit
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Interactome
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Pathway
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Disease
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