KCNMB4 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-KCNMB4 full-length
Host
Human
Theoretical MW (kDa)
23.9
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-KCNMB4 antibody (H00027345-D01P) by Western Blots.
SDS-PAGE Gel
KCNMB4 transfected lysate.
Western Blot
Lane 1: KCNMB4 transfected lysate ( 23.9 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — KCNMB4
Entrez GeneID
27345GeneBank Accession#
NM_014505Protein Accession#
NP_055320.4Gene Name
KCNMB4
Gene Alias
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Gene Description
potassium large conductance calcium-activated channel, subfamily M, beta member 4
Omim ID
605223Gene Ontology
HyperlinkGene Summary
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit. [provided by RefSeq
Other Designations
calcium-activated potassium channel beta 4 subunit|large conductance calcium-dependent potassium ion channel beta 4 subunit
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Interactome
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Disease
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