KCNMB4 monoclonal antibody (M01), clone 1G7
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant KCNMB4.
Immunogen
KCNMB4 (AAH50621, 1 a.a. ~ 210 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAKLRVAYEYTEAEDKSIRLGLFLIISGVVSLFIFGFCWLSPALQDLQATEANCTVLSVQQIGEVFECTFTCGADCRGTSQYPCVQVYVNNSESNSRALLHSDEHQLLTNPKCSYIPPCKRENQKNLESVMNWQQYWKDEIGSQPFTCYFNQHQRPDDVLLHRTHDEIVLLHCFLWPLVTFVVGVLIVVLTICAKSLAVKAEAMKKRKFS
Host
Mouse
Reactivity
Human
Isotype
IgG1 kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged KCNMB4 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — KCNMB4
Entrez GeneID
27345GeneBank Accession#
BC050621Protein Accession#
AAH50621Gene Name
KCNMB4
Gene Alias
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Gene Description
potassium large conductance calcium-activated channel, subfamily M, beta member 4
Omim ID
605223Gene Ontology
HyperlinkGene Summary
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which slows activation kinetics, leads to steeper calcium sensitivity, and shifts the voltage range of current activation to more negative potentials than does the beta 1 subunit. [provided by RefSeq
Other Designations
calcium-activated potassium channel beta 4 subunit|large conductance calcium-dependent potassium ion channel beta 4 subunit
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Interactome
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Pathway
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Disease
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