RABGEF1 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human RABGEF1 protein.
Immunogen
RABGEF1 (NP_055319.1, 1 a.a. ~ 491 a.a) full-length human protein.
Sequence
MSLKSERRGIHVDQSDLLCKKGCGYYGNPAWQGFCSKCWREEYHKARQKQIQEDWELAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFSASSRVGSKKEIQEAKAPSPSINRQTSIETDRVSKEFIEFLKTFHKTGQEIYKQTKLFLEGMHYKRDLSIEEQSECAQDFYHNVAERMQTRGKVPPERVEKIMDQIEKYIMTRLYKYVFCPETTDDEKKDLAIQKRIRALRWVTPQMLCVPVNEDIPEVSDMVVKAITDIIEMDSKRVPRDKLACITKCSKHIFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCAVAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQEAESWSPDACLGVKQMYKNLDLLSQLNERQERIMNEAKKLEKDLIDWTDGIAREVQDIVEKYPLEIKPPNQPLAAIDSENVENDKLPPPLQPQVYAG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
RABGEF1 MaxPab polyclonal antibody. Western Blot analysis of RABGEF1 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of RABGEF1 expression in transfected 293T cell line (H00027342-T02) by RABGEF1 MaxPab polyclonal antibody.
Lane 1: RABGEF1 transfected lysate(54.01 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — RABGEF1
Entrez GeneID
27342GeneBank Accession#
NM_014504Protein Accession#
NP_055319.1Gene Name
RABGEF1
Gene Alias
FLJ32302, RABEX5, rabex-5
Gene Description
RAB guanine nucleotide exchange factor (GEF) 1
Omim ID
609700Gene Ontology
HyperlinkGene Summary
RABGEF1 forms a complex with rabaptin-5 (RABPT5; MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor for RAB5 (RAB5A; MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).[supplied by OMIM
Other Designations
Rab5 GDP/GTP exchange factor
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Interactome
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Disease
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