ANGPTL3 (Human) IP-WB Antibody Pair
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (76); Rat (80)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of ANGPTL3 transfected lysate using mouse monoclonal anti-ANGPTL3 and Protein A Magnetic Bead (U0007), and immunoblotted with rabbit polyclonal anti-ANGPTL3.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: mouse monoclonal anti-ANGPTL3 (300 ug)
2. Antibody pair for WB: rabbit polyclonal anti-ANGPTL3 (50 ul)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — ANGPTL3
Entrez GeneID
27329Gene Name
ANGPTL3
Gene Alias
ANGPT5
Gene Description
angiopoietin-like 3
Omim ID
604774Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. [provided by RefSeq
Other Designations
OTTHUMP00000010719|angiopoietin 5
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Interactome
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