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APEX2 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00027301-T01
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-APEX2 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 57.09
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-APEX2 antibody (H00027301-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00027301-T01
    APEX2 transfected lysate.
    Western Blot
    QC Testing of H00027301-T01
    Lane 1: APEX2 transfected lysate ( 57.09 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Gene Name:
  • APEX2
  • Gene Alias:
  • Gene Description:
  • APEX nuclease (apurinic/apyrimidinic endonuclease) 2
  • Gene Summary:
  • Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair (BER). [provided by RefSeq
  • Other Designations:
  • APEX nuclease-like 2,OTTHUMP00000023390,OTTHUMP00000061908,apurinic/apyrimidinic endonuclease 2,apurinic/apyrimidinic endonuclease-like 2
  • Gene Pathway
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