PDLIM3 (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human PDLIM3 full-length ORF ( AAH27870, 1 a.a. - 316 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHNRRAQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALHGQLRGLIPSSPQNEPTASVPPESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTLYPKA
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
60.5
Interspecies Antigen Sequence
Rat (68)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — PDLIM3
Entrez GeneID
27295GeneBank Accession#
BC027870Protein Accession#
AAH27870Gene Name
PDLIM3
Gene Alias
ALP, DKFZp686L0362
Gene Description
PDZ and LIM domain 3
Omim ID
605889Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. This gene is found near a region of chromosome 4 that has been implicated in facioscapulohumeral muscular dystrophy, but this gene does not appear to be involved in the disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
PDZ and LIM domain protein 3|alpha-actinin-2-associated LIM protein|enigma homolog
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Interactome
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Disease
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