Products

Western Blot (Cell lysate)

HNRNPG-T monoclonal antibody (M01), clone 6F11 Western Blot analysis of HNRNPG-T expression in HeLa ( Cat # L013V1 ).

Western Blot (Recombinant protein)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)

Immunoperoxidase of monoclonal antibody to HNRNPG-T on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml]

Sandwich ELISA (Recombinant protein)

Detection limit for recombinant GST tagged HNRNPG-T is approximately 0.1ng/ml as a capture antibody.

ELISA

Immunofluorescence

Immunofluorescence of monoclonal antibody to HNRNPG-T on HeLa cell. [antibody concentration 10 ug/ml]

Entrez GeneID

27288

GeneBank Accession#

NM_014469

Protein Accession#

NP_055284

Gene Name

RBMXL2

Gene Alias

HNRNPG-T, HNRNPGT, HNRPGT

Gene Description

RNA binding motif protein, X-linked-like 2

Omim ID

605444

Gene Ontology

Hyperlink

Gene Summary

This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility. [provided by RefSeq

Other Designations

heterogeneous nuclear ribonucleoprotein G T|testes specific heterogenous nuclear ribonucleoprotein G T|testes-specific heterogenous nuclear ribonucleoprotein G-T