GPR77 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human GPR77 protein.
Immunogen
GPR77 (NP_060955.1, 1 a.a. ~ 337 a.a) full-length human protein.
Sequence
MGNDSVSYEYGDYSDLSDRPVDCLDGACLAIDPLRVAPLPLYAAIFLVGVPGNAMVAWVAGKVARRRVGATWLLHLAVADLLCCLSLPILAVPIARGGHWPYGAVGCRALPSIILLTMYASVLLLAALSADLCFLALGPAWWSTVQRACGVQVACGAAWTLALLLTVPSAIYRRLHQEHFPARLQCVVDYGGSSSTENAVTAIRFLFGFLGPLVAVASCHSALLCWAARRCRPLGTAIVVGFFVCWAPYHLLGLVLTVAAPNSALLARALRAEPLIVGLALAHSCLNPMLFLYFGRAQLRRSLPAACHWALRESQGQDESVDSKKSTSHDLVSEMEV
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Flow Cytometry
FACS analysis of negative control 293 cells (Black) and GPR77 expressing 293 cells (Green) using GPR77 purified MaxPab mouse polyclonal antibody.Western Blot (Transfected lysate)
Western Blot analysis of GPR77 expression in transfected 293T cell line (H00027202-T01) by GPR77 MaxPab polyclonal antibody.
Lane 1: GPR77 transfected lysate(37.07 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — GPR77
Entrez GeneID
27202GeneBank Accession#
NM_018485.1Protein Accession#
NP_060955.1Gene Name
GPR77
Gene Alias
C5L2, GPF77
Gene Description
G protein-coupled receptor 77
Omim ID
609949Gene Ontology
HyperlinkGene Summary
The anaphylatoxins C3a (see MIM 120700), C4a (see MIM 120810), and C5a are cationic fragments generated during the complement cascade that participate in host defense. In the case of inappropriate complement activation, anaphylatoxins may be involved in autoimmunity and sepsis. C5L2 is coexpressed with the C5a receptor, C5AR (C5R1; MIM 113995), on polymorphonuclear neutrophils and may modulate C5AR activity (Gerard et al., 2005 [PubMed 16204243]).[supplied by OMIM
Other Designations
G protein-coupled receptor C5L2
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Interactome
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Pathway
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