VPS4A purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of VPS4A expression in transfected 293T cell line (H00027183-T01) by VPS4A MaxPab polyclonal antibody.
Lane 1: VPS4A transfected lysate(48.07 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human VPS4A protein.
Immunogen
VPS4A (NP_037377.1, 1 a.a. ~ 437 a.a) full-length human protein.
Sequence
MTTSTLQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKYEAHSDKAKESIRAKCVQYLDRAEKLKDYLRSKEKHGKKPVKENQSEGKGSDSDSEGDNPEKKKLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENESEAARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPVRKVQSATHFKKVCGPSRTNPSMMIDDLLTPCSPGDPGAMEMTWMDVPGDKLLEPVVCMSDMLRSLATTRPTVNADDLLKVKKFSEDFGQES
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of VPS4A expression in transfected 293T cell line (H00027183-T01) by VPS4A MaxPab polyclonal antibody.
Lane 1: VPS4A transfected lysate(48.07 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — VPS4A
Entrez GeneID
27183GeneBank Accession#
NM_013245.2Protein Accession#
NP_037377.1Gene Name
VPS4A
Gene Alias
FLJ22197, SKD1, SKD2, VPS4, VPS4-1
Gene Description
vacuolar protein sorting 4 homolog A (S. cerevisiae)
Omim ID
609982Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16; the gene for the other resides on chromosome 18. [provided by RefSeq
Other Designations
SKD1-homolog|vacuolar protein sorting factor 4A|vacuolar sorting protein 4
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Interactome
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Pathway
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