The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations:
IL-1F8 (FIL1-eta),IL1F8 (Canonical product IL-1F8a),Interleukin-1 Superfamily e,family of interleukin 1-eta,interleukin 1 family, member 8,interleukin 1, eta,interleukin-1 homolog 2