MORC1 monoclonal antibody (M09), clone 3E8
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MORC1.
Immunogen
MORC1 (NP_055244, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MDDRYPALQRAQLRLDFIHANSTTHSFLFGALAELLDNARDAGAERLDVFSVDNEKLQGGFMLCFLDDGCGMSPEEASDIIYFGRSKKRLSTLKFIGQYG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (66); Rat (67)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
MORC1 monoclonal antibody (M09), clone 3E8. Western Blot analysis of MORC1 expression in HepG2(Cat # L019V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MORC1 is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — MORC1
Entrez GeneID
27136GeneBank Accession#
NM_014429Protein Accession#
NP_055244Gene Name
MORC1
Gene Alias
MORC, ZCW6
Gene Description
MORC family CW-type zinc finger 1
Omim ID
603205Gene Ontology
HyperlinkGene Summary
This gene encodes the human homolog of mouse morc and like the mouse protein it is testis-specific. Mouse studies support a testis-specific function since only male knockout mice are infertile; infertility is the only apparent defect. These studies further support a role for this protein early in spermatogenesis, possibly by affecting entry into apoptosis because testis from knockout mice show greatly increased numbers of apoptotic cells. [provided by RefSeq
Other Designations
microrchidia homolog|microrchidia, mouse, homolog of|microrchidia, mouse, honolog of
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Interactome
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Disease
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