INVS polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (36.12 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant INVS.
Immunogen
INVS (NP_055240, 1 a.a. ~ 91 a.a) partial recombinant protein with GST tag.
Sequence
MNKSENLLFAGSSLASQVHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTALHLAAQK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90); Rat (94)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.12 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — INVS
Entrez GeneID
27130GeneBank Accession#
NM_014425Protein Accession#
NP_055240Gene Name
INVS
Gene Alias
INV, KIAA0573, MGC133080, MGC133081, NPH2, NPHP2
Gene Description
inversin
Gene Ontology
HyperlinkGene Summary
This gene encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in this gene have been associated with nephronophthisis type 2. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000021790|OTTHUMP00000063824|inversion of embryonic turning
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Interactome
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Publication Reference
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Altered modulation of WNT?Vb-catenin and PI3K/Akt pathways in IgA.
Cox SN, Sallustio F, Serino G, Pontrelli P, Verrienti R, Pesce F, Torres DD, Ancona N, Stifanelli P, Zaza G, Schena FP.
Kidney International 2010 Aug; 78(4):396.
Application：WB-Ce, Human, PBMCs.
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Altered modulation of WNT?Vb-catenin and PI3K/Akt pathways in IgA.
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