DKK2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human DKK2 full-length ORF (BAG35574.1, 1 a.a. - 259 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAALMRSKDSSCCLLLLAAVLMVESSQIGSSRAKLNSIKSSLGGETPGQAANRSAGMYQGLAFGGSKKGKNLGQAYPCSSDKECEVGRYCHSPHQGSSACMVCRRKKKRCHRDGMCCPSTRCNNGICIPVTESILTPHIPALDGTRHRDRNHGHYSNHDLGWQNLGRPHTKMSHIKGHEGDPCLRSSDCIEGFCCARHFWTKICKPVLHQGEVCTKQRKKGSHGLEIFQRCDCAKGLSCKVWKDATYSSKARLHVCQKI
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
54.89
Interspecies Antigen Sequence
Mouse (94); Rat (95)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — DKK2
Entrez GeneID
27123GeneBank Accession#
AK312695.1Protein Accession#
BAG35574.1Gene Name
DKK2
Gene Alias
DKK-2
Gene Description
dickkopf homolog 2 (Xenopus laevis)
Omim ID
605415Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq
Other Designations
dickkopf 2|dickkopf homolog 2|dickkopf related protein-2
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Interactome
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Pathway
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Disease
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