DKK3 (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human DKK3 full-length ORF ( AAH07660.1, 1 a.a. - 350 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MQRLGATLLCLLLAAAVPTAPAPAPTATSAPVKPGPALSYPQEEATLNEMFREVEELMEDTQHKLRSAVEEMEAEEAAAKASSEVNLANLPPSYHNETNTDTKVGNNTIHVHREIHKITNNQTGQMVFSETVITSVGDEEGRRSHECIIDEDCGPSMYCQFASFQYTCQPCRGQRMLCTRDSECCGDQLCVWGHCTKMATRGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTPLPVEGELCHDPASRLLDLITWELEPDGALDRCPCASGLLCQPHSHSLVYVCKPTFVGSRDQDGEILLPREVPDEYEVGSFMEEVRQELEDLERSLTEEMALGEPAAAAAALLGGEEI
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
64.7
Interspecies Antigen Sequence
Mouse (82); Rat (79)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — DKK3
Entrez GeneID
27122GeneBank Accession#
BC007660.2Protein Accession#
AAH07660.1Gene Name
DKK3
Gene Alias
REIC
Gene Description
dickkopf homolog 3 (Xenopus laevis)
Omim ID
605416Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
Other Designations
RIG-like 5-6|RIG-like 7-1|dickkopf 3|dickkopf homolog 3
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Interactome
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Disease
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