PDE7B 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-PDE7B full-length
Host
Human
Theoretical MW (kDa)
49.61
Interspecies Antigen Sequence
Mouse (91); Rat (90)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-PDE7B antibody (H00027115-B01) by Western Blots.
SDS-PAGE Gel
PDE7B transfected lysate.
Western Blot
Lane 1: PDE7B transfected lysate ( 49.61 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — PDE7B
Entrez GeneID
27115GeneBank Accession#
NM_018945.3Protein Accession#
NP_061818.1Gene Name
PDE7B
Gene Alias
MGC88256, bA472E5.1
Gene Description
phosphodiesterase 7B
Omim ID
604645Gene Ontology
HyperlinkGene Summary
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family
Other Designations
OTTHUMP00000017267|high-affinity cAMP-specific 3',5'-cyclic phosphodiesterase|rolipram-insensitive phosphodiesterase type 7
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