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Last updated: 2017/4/30

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PDE7B rabbit monoclonal antibody

  • Catalog # : H00027115-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PDE7B peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PDE7B is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PDE7B peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • GeneBank Accession#:
  • PDE7B
  • Gene Name:
  • PDE7B
  • Gene Alias:
  • MGC88256,bA472E5.1
  • Gene Description:
  • phosphodiesterase 7B
  • Gene Summary:
  • The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family
  • Other Designations:
  • OTTHUMP00000017267,high-affinity cAMP-specific 3',5'-cyclic phosphodiesterase,rolipram-insensitive phosphodiesterase type 7
  • Gene Pathway
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