Immunoprecipitation of CACYBP transfected lysate using anti-CACYBP MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with CACYBP purified MaxPab mouse polyclonal antibody (B01P) (H00027101-B01P).
The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
OTTHUMP00000032884,OTTHUMP00000032885,Siah-interacting protein (SIP),growth-inhibiting gene 5 protein