KCNMB3 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human KCNMB3 partial ORF ( NP_741979, 82 a.a. - 181 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNG
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (70); Rat (77)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — KCNMB3
Entrez GeneID
27094GeneBank Accession#
NM_171828Protein Accession#
NP_741979Gene Name
KCNMB3
Gene Alias
KCNMB2, KCNMBL
Gene Description
potassium large conductance calcium-activated channel, subfamily M beta member 3
Omim ID
605222Gene Ontology
HyperlinkGene Summary
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22. [provided by RefSeq
Other Designations
calcium-activated potassium channel beta 3 subunit|large conductance, voltage and Ca2+ activated potassium channel Maxi K beta 3 subunit|potassium large conductance calcium-activated channel beta 3 subunit
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Interactome
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Pathway
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Disease
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