KCNMB3 monoclonal antibody (M02), clone 5H1
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged KCNMB3 is approximately 0.3ng/ml as a capture antibody.
Western Blot detection against Immunogen (36.74 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant KCNMB3.
Immunogen
KCNMB3 (NP_741979, 82 a.a. ~ 181 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
FMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQKALLHYNEEAVQINPKCFYTPKCHQDRNDLLNSALDIKEFFDHKNG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (70); Rat (77)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged KCNMB3 is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — KCNMB3
Entrez GeneID
27094GeneBank Accession#
NM_171828Protein Accession#
NP_741979Gene Name
KCNMB3
Gene Alias
KCNMB2, KCNMBL
Gene Description
potassium large conductance calcium-activated channel, subfamily M beta member 3
Omim ID
605222Gene Ontology
HyperlinkGene Summary
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22. [provided by RefSeq
Other Designations
calcium-activated potassium channel beta 3 subunit|large conductance, voltage and Ca2+ activated potassium channel Maxi K beta 3 subunit|potassium large conductance calcium-activated channel beta 3 subunit
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Interactome
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Pathway
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Disease
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