LAT polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (51.74 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length recombinant LAT.
Immunogen
LAT (AAH11563, 1 a.a. ~ 233 a.a) full-length recombinant protein with GST tag.
Sequence
MEEAILVPCVLGLLLLPILAMLMALCVHCHRLPGSYDSTSSDSLYPRGIQFKRPHTVAPWPPAYPPVTSYPPLSQPDLLPIPRSPQPLGGPHRTPSSRRDSDGANSVASYENEEPACEDADEDEDDYHNPGYLVVLPDSTPATSTAAPSAPALSTPGIRDSAFSMESIDDYVNVPESGESAEASLDGSREYVNVSQELHPGAAKTEPAALSSQEAEEVEEEGAPDYENLQELN
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (51.74 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — LAT
Entrez GeneID
27040GeneBank Accession#
BC011563Protein Accession#
AAH11563Gene Name
LAT
Gene Alias
LAT1, pp36
Gene Description
linker for activation of T cells
Omim ID
602354Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
36 kDa phospho-tyrosine adaptor protein
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Interactome
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Pathway
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