NOX1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human NOX1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human NOX1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human NOX1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — NOX1
Entrez GeneID
27035GeneBank Accession#
NOX1Gene Name
NOX1
Gene Alias
GP91-2, MOX1, NOH-1, NOH1
Gene Description
NADPH oxidase 1
Omim ID
300225Gene Ontology
HyperlinkGene Summary
Voltage-gated proton (hydrogen) channels play an important role in cellular defense against acidic stress. They are unique among ion channels with respect to their extremely high selectivity, marked temperature dependence, and unitary conductance, which is 3 orders of magnitude lower than that of most other ion channels. NOX1 is a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
NADPH oxidase 1 variant NOH-1L|NADPH oxidase homolog-1|OTTHUMP00000023657|OTTHUMP00000023659|mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating)
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