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Last updated: 2017/9/24

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MLH3 Pre-design Chimera RNAi

  • Catalog # : H00027030-R01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Homo sapiens mutL homolog 3 (E. coli) (MLH3), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_014381
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Gene Name:
  • MLH3
  • Gene Alias:
  • HNPCC7,MGC138372
  • Gene Description:
  • mutL homolog 3 (E. coli)
  • Gene Summary:
  • This gene is a member of the MutL-homolog (MLH) family of DNA mismatch repair (MMR) genes. MLH genes are implicated in maintaining genomic integrity during DNA replication and after meiotic recombination. The protein encoded by this gene functions as a heterodimer with other family members. Somatic mutations in this gene frequently occur in tumors exhibiting microsatellite instability, and germline mutations have been linked to hereditary nonpolyposis colorectal cancer type 7 (HNPCC7). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq
  • Other Designations:
  • DNA mismatch repair protein MLH3,mutL homolog 3
  • Gene Pathway
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