DNAI1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human DNAI1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human DNAI1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human DNAI1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — DNAI1
Entrez GeneID
27019GeneBank Accession#
DNAI1Gene Name
DNAI1
Gene Alias
CILD1, ICS, ICS1, MGC26204, PCD
Gene Description
dynein, axonemal, intermediate chain 1
Gene Ontology
HyperlinkGene Summary
The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. This gene encodes an intermediate chain dynein, belonging to the large family of motor proteins. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia (PCD) and Kartagener syndrome. [provided by RefSeq
Other Designations
OTTHUMP00000021280|dynein intermediate chain DNAI1|dynein, axonemal, intermediate polypeptide 1|immotile cilia syndrome 1
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Interactome
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Disease
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