ZRF1 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human ZRF1 full-length ORF ( AAH56682.1, 1 a.a. - 167 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MLLLPSAADGRGTAITHALTSASTLCQVEPVGRWFEAFVKRRNRNASASFQELEDKKELSEESEDEELQLEEFPMLKTLDPKDWKNQDHYAVLGLGHVRYKATQRQIKAAHKAMVLKHHPDKRKAAGEPIKEGDNDYFTCITKGSPGDSYQKLILQLIHLMKCYLIQ
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
45.4
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — DNAJC2
Entrez GeneID
27000GeneBank Accession#
BC056682.1Protein Accession#
AAH56682.1Gene Name
DNAJC2
Gene Alias
MPHOSPH11, MPP11, ZRF1, ZUO1
Gene Description
DnaJ (Hsp40) homolog, subfamily C, member 2
Omim ID
605502Gene Ontology
HyperlinkGene Summary
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq
Other Designations
M-phase phosphoprotein 11|zuotin related factor 1
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