ZRF1 monoclonal antibody (M09), clone 3F2
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant ZRF1.
Immunogen
ZRF1 (XP_168590.4, 408 a.a. ~ 508 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LDPHQKDDINKKAFDKFKKEHGVVPQADNATPSERFEGPYTDFTPWTTEEQKLLEQALKTYPVNTPERWEKIAEAVPGRTKKDCMKRYKELVEMVKAKKAA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.85 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged DNAJC2 is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — DNAJC2
Entrez GeneID
27000GeneBank Accession#
XM_168590Protein Accession#
XP_168590.4Gene Name
DNAJC2
Gene Alias
MPHOSPH11, MPP11, ZRF1, ZUO1
Gene Description
DnaJ (Hsp40) homolog, subfamily C, member 2
Omim ID
605502Gene Ontology
HyperlinkGene Summary
This gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq
Other Designations
M-phase phosphoprotein 11|zuotin related factor 1
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