PABPC1 purified MaxPab rabbit polyclonal antibody (D01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of PABPC1 expression in transfected 293T cell line (H00026986-T02) by PABPC1 MaxPab polyclonal antibody.
Lane 1: PABPC1 transfected lysate(70.70 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PABPC1 on HeLa cell. [antibody concentration 20 ug/ml]
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PABPC1 protein.
Immunogen
PABPC1 (NP_002559.2, 1 a.a. ~ 636 a.a) full-length human protein.
Sequence
MNPSAPSYPMASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALAQRKEERQAHLTNQYMQRMASVRAVPNPVINPYQPAPPSGYFMAAIPQTQNRAAYYPPSQIAQLRPSPRWTAQGARPHPFQNMPGAIRPAAPRPPFSTMRPASSQVPRVMSTQRVANTSTQTMGPRPAAAAAAATPAVRTVPQYKYAAGVRNPQQHLNAQPQVTMQQPAVHVQGQEPLTASMLASAPPQEQKQMLGERLFPLIQAMHPTLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQAHQAKEAAQKAVNSATGVPTV
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PABPC1 expression in transfected 293T cell line (H00026986-T02) by PABPC1 MaxPab polyclonal antibody.
Lane 1: PABPC1 transfected lysate(70.70 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PABPC1 on HeLa cell. [antibody concentration 20 ug/ml] -
Gene Info — PABPC1
Entrez GeneID
26986GeneBank Accession#
NM_002568.3Protein Accession#
NP_002559.2Gene Name
PABPC1
Gene Alias
PAB1, PABP, PABP1, PABPC2, PABPL1
Gene Description
poly(A) binding protein, cytoplasmic 1
Omim ID
604679Gene Ontology
HyperlinkGene Summary
The poly(A)-binding protein (PABP), which is found complexed to the 3-prime poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4; MIM 603407), and PABP3 (PABPC3; MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.[supplied by OMIM
Other Designations
poly(A) binding protein, cytoplasmic 2|poly(A)-binding protein, cytoplasmic 2
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Interactome
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Publication Reference
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Spatio-temporal uncoupling of miRNA-mediated translational repression and target RNA degradation controls miRNP recycling in mammalian cells.
Bose M, Barman B, Goswami A, Bhattacharyya SN.
Molecular and Cellular Biology 2016 Nov; [Epub].
Application：WB-Tr, Human, HeLa, HEK 293 cells.
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A Novel Small Compound That Promotes Nuclear Translocation of YB-1 Ameliorates Experimental Hepatic Fibrosis in Mice.
Higashi K, Tomigahara Y, Shiraki H, Miyata K, Mikami T, Kimura T, Moro T, Inagaki Y, Kaneko H.
The Journal of Biological Chemistry 2011 Feb; 286(6):4485.
Application：WB, Human, Fibroblasts.
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Spatio-temporal uncoupling of miRNA-mediated translational repression and target RNA degradation controls miRNP recycling in mammalian cells.
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