NBEA monoclonal antibody (M01), clone 3F11
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant NBEA.
Immunogen
NBEA (NP_056493.3, 1133 a.a. ~ 1220 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ADEKEDLPNSSTSFLFDKIPKQEEKLLPELSSNHIIPNIQDTQVHLGVSDDLGLLAHMTGSVDLTCTSSIIEEKEFKIHTTSDGMSSI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.42 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged NBEA is 0.3 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to NBEA on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — NBEA
Entrez GeneID
26960GeneBank Accession#
NM_015678Protein Accession#
NP_056493.3Gene Name
NBEA
Gene Alias
BCL8B, LYST2
Gene Description
neurobeachin
Omim ID
604889Gene Ontology
HyperlinkGene Summary
This gene encodes a member of a large, diverse group of A-kinase anchor proteins that target the activity of protein kinase A to specific subcellular sites by binding to its type II regulatory subunits. Brain-specific expression and coat protein-like membrane recruitment of a highly similar protein in mouse suggest an involvement in neuronal post-Golgi membrane traffic. Mutations in this gene may be associated with a form of autism. Alternatively spliced transcript variants may exist, but their full-length nature has not been determined. [provided by RefSeq
Other Designations
lysosomal trafficking regulator 2
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Interactome
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Disease
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